Abciximab is administered by which route?

Abciximab is administered by which route?

• A. Intravenous
• B. Oral
• C. Topical
• D. Subcutaneous

Answer: (A)

Abciximab is a monoclonal antibody fragment used to rapidly inhibit platelet aggregation by blocking the GPIIb/IIIa receptor. Because it is a large protein, it would be broken down in the digestive system and not absorbed if taken by mouth, making oral administration ineffective. For immediate and controllable effect during procedures like PCI, it needs direct entry into the bloodstream, so it is given intravenously. Other routes (oral, topical, or subcutaneous) would result in poor or inconsistent absorption and a much slower onset, which isn’t suitable for this drug’s purpose.

Abciximab is a monoclonal antibody fragment used to rapidly inhibit platelet aggregation by blocking the GPIIb/IIIa receptor. Because it is a large protein, it would be broken down in the digestive system and not absorbed if taken by mouth, making oral administration ineffective. For immediate and controllable effect during procedures like PCI, it needs direct entry into the bloodstream, so it is given intravenously. Other routes (oral, topical, or subcutaneous) would result in poor or inconsistent absorption and a much slower onset, which isn’t suitable for this drug’s purpose.