Which symptom is commonly monitored as a side effect of GM-CSF therapy?

Which symptom is commonly monitored as a side effect of GM-CSF therapy?

• A. Hearing loss
• B. Jaundice
• C. Diarrhea
• D. Hypotension

Answer: (C)

GM-CSF stimulates production of neutrophils and macrophages, which can affect rapidly dividing tissues including the GI tract. Diarrhea is a common and important symptom to monitor because it can reflect GI irritation from the therapy and may lead to dehydration or electrolyte imbalances if not managed. Regular checks of bowel habits help ensure any side effects are caught early and treated appropriately. Hearing loss, jaundice, and hypotension aren’t typical or primary concerns with GM-CSF therapy, so they’re not the symptoms clinicians focus on for routine monitoring in this context.

GM-CSF stimulates production of neutrophils and macrophages, which can affect rapidly dividing tissues including the GI tract. Diarrhea is a common and important symptom to monitor because it can reflect GI irritation from the therapy and may lead to dehydration or electrolyte imbalances if not managed. Regular checks of bowel habits help ensure any side effects are caught early and treated appropriately. Hearing loss, jaundice, and hypotension aren’t typical or primary concerns with GM-CSF therapy, so they’re not the symptoms clinicians focus on for routine monitoring in this context.